Pathology Questions-3

A 67-year-old woman presents with a 4-week
history of headaches, facial pain, blurred
vision, and intense pain and stiffness in her
shoulders and hips. She is diagnosed with a
vasculitis, and a biopsy of an affected artery is
taken. Histological examination is most likely
to reveal which of the following characteristic
findings?
(A) concentric “onion skin” thickening and
fibrosis
(B) extensive intra- and extravascular granulomatous
inflammation
(C) fragmentation of the internal elastic
lamina with giant cells
(D) hyaline arteriolosclerosis and luminal
narrowing
(E) segmental fibrinoid necrosis and neutrophil
infiltration

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