Microbiology Questions-11

Over several years, an 11-year-old student
developed multiple infections caused by organisms
normally of low virulence (Staphylococcus
epidermidis, Aspergillus) and was diagnosed as
having chronic granulomatous disease (CGD).
This immune deficiency is due to which of the
following?
(A) inability of neutrophils to kill bacteria
(B) inability of phagosomes to fuse with
lysosomes
(C) inability of polymorphonuclear leucocytes
to ingest bacteria
(D) loss of complement components
(E) reduced levels of immumoglobulins

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