A 2-year-old male patient develops progressive
generalized weakness and muscle atrophy.
The impairment first began with the muscles of
the hips, and then progressed to the pelvic area,
thigh, and shoulder muscles. The patient is
diagnosed with Duchenne’s muscular dystrophy,
a congenital disorder where the protein
dystrophin is deficient. Which of the following
describes the role of dystrophin in muscle
tissue?
(A) anchors actin to the sarcolemma
(B) endows the myosin filaments with elastic
recoil properties
(C) extends from Z disk to Zdisk, forming a
supportive network
(D) inhibits the binding of myosin to actin
(E) protects desmin filaments from stressinduced
damage
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Friday, October 28, 2011
Anatomy-1
10:53 AM
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